Monday, December 06, 2004

Sickle Cell Clinical Study Halted

Risk of Strokes Halts Sickle Cell Study
By Daniel Yee
Associated Press
The Washington Post
Monday, December 6, 2004; Page A02

ATLANTA, Dec. 5 -- A study aimed at determining whether some children with sickle cell anemia could be weaned off blood transfusion therapy has been halted because two young patients who stopped getting the procedure suffered strokes and others developed a high chance of strokes.

The National Institutes of Health decided to issue a clinical alert recommending that doctors continue with blood transfusions to reduce the risk of stroke among young sickle cell patients, even though the treatment has its own risk.

The study, called Stop II, was funded by the NIH's National Heart, Lung, and Blood Institute and involved 23 U.S. medical centers and two in Canada.

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